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buy Oxynorm 20mg Oxycodone, which is sold under the Oxynorm brand , is an opioid drug used to treat moderate to severe pain and a common addictive drug. [12] [13] It is usually taken orally and is available in immediate release and controlled release formulations. [12] The onset of pain relief usually begins within 15 minutes and lasts for up to six hours with the immediate release formulation. [12] In the UK, it is available by injection. [14] Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone and aspirin. [12]

Common side effects include constipation, nausea, drowsiness, dizziness, itching, dry mouth and sweating. [12] Serious side effects may include substance abuse, respiratory depression (decreased respiration) and low blood pressure. [12] Those who are allergic to codin may also be allergic to oxycodone. [12] The use of oxycodone in early pregnancy appears relatively safe. [12] Opioid withdrawal can occur if stopped quickly. [12] Oxycodone acts by activating the μ-opioid receptor. [15] When taken orally, it has approximately 1.5 times the effect of the corresponding amount of morphine. [16]

Oxycodone was first manufactured in Germany in 1916 from thebaine. [17] It is available as a generic medicine. [12] In the United States, the wholesale cost per dose is less than $ 0.30 as of 2018. [18] In 2017, it was the 52nd most commonly prescribed drug in the United States, with more than 15 million prescriptions. [19] [20] A number of formulations for deterrent abuse are available, for example in combination with naloxone. [13] [21]